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Table 1 Patient characteristics

From: Trastuzumab-based palliative chemotherapy for HER2-positive gastric cancer: a single-center real-world data

Clinical characteristics Total (n = 47)
Age, years
  < 70 37 (79%)
  ≥ 70 10 (21%)
Gender
 Male 38 (81%)
 Female 9 (19%)
ECOG PS
 0 12 (25%)
 1 28 (60%)
 2 7 (15%)
Disease status
 Primary metastatic 36 (77%)
 Recurrent 11 (23%)
Histology
 Well or moderately differentiated 21 (45%)
 Poorly differentiated 18 (38%)
 Signet ring cell 4 (9%)
 Combined, others 4 (9%)
HER2 status
 IHC 3+ 40 (85%)
 IHC 2+ with SISH + 7 (15%)
Liver metastasis
 No 23 (49%)
 Yes 24 (51%)
Peritoneal metastasis
 No 32 (68%)
 Yes 15 (32%)
Amount of ascites
    No 26 (55%)
 Small or moderate 16 (34%)
 Massive 5 (11%)
Surgical resection
 No 38 (81%)
 Yesa 9 (19%)
  1. ECOG Eastern Cooperative Oncology Group, PS performance status, HER2 human epidermal growth factor receptor 2, IHC immunohistochemistry, SISH silver-enhanced in situ hybridization
  2. aincluding 6 patients who underwent surgery after chemotherapy